Tasleem, Shuwana and Bomma, Satish Kumar (2023) Simulation Studies on Recovery of Acetonitrile from Aqueous Acetonitrile Waste from Pharmaceutical Processes. Asian Journal of Chemical Sciences, 13 (2). pp. 34-46. ISSN 2456-7795
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Abstract
This paper presents simulation studies on the recovery of Acetonitrile from aqueous Acetonitrile waste from pharmaceutical processes. The focus is on atmospheric distillation in two sequential columns to understand the separation feasibility of the system; the first column produces a distillate of azeotropic composition, which is mixed with a fresh stream and fed to a second column, which produces a 99.9% pure Acetonitrile in the residue. The effect of reflux ratio, reboiler duty and the fresh stream flowrate on the purity of the product is analyzed. The study was performed using steady state simulator Aspen Plus, version 11.1. The simulation results indicate that it is possible to obtain a product of 99.9% w/w Acetonitrile from a 1:1 feed with a recovery of ~ 60%.
Item Type: | Article |
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Subjects: | Research Asian Plos > Chemical Science |
Depositing User: | Unnamed user with email support@research.asianplos.com |
Date Deposited: | 18 May 2023 12:18 |
Last Modified: | 07 Aug 2024 06:09 |
URI: | http://global.archiveopenbook.com/id/eprint/893 |